Saturday, December 27, 2014

On Prader-willi like issue

My question is simply is a lesser form of Prander-willi possible? Prader-willi is the result of a group of  genetic deformation. If only one or small amount of that group occurs, then what?

Quotes from about the web:

The reasons for abnormal eating remain unclear and effective treatments are lacking. Ghrelin, the most powerful hunger hormone, is markedly raised in some and is the likely cause of overeating. 

In individuals who are obese, including those with a biological predilection for excessive eating due to delayed satiety response.

Individuals are noted for relent-less food seeking (e.g., hoarding, foraging for food) if free access to food is denied, and their insatiable appetite may lead to maladaptive behavior(e.g., stealing food or money to buy food, aggressive behavior). If food is readily available, however, it may lead to life-threatening obesity because of overeating, low metabolic rate, and decreased activity.

Hunger does not appear to be the issue, rather heightened visual stimulation, combined with availability. Allow them one cookie, and they will eat the whole plate. Address the visual stimulation is the most important part of treatment. Ideally, there should be no visual stimulation. 

But, but, other than high Ghrenlin, which I do not know about, this describes my issues.

Protein in diet suppresses ghrelin
Diets high in protein are a good way to keep hunger in check. Protein in the diet is effective at keeping ghrelin in check, while carbohydrates and fats don't work that well. Suppression of ghrelin is a way to lose appetite. Fats suppress ghrelin quite poorly. Proteins suppress ghrelin quite well. Carbohydrates suppress ghrelin well at first, but levels rebound later, rising to an even higher level. Carbohydrates eventually make people even hungrier than before they had eaten. (


Wisewebwoman said...

Yup. It describes me to a T. Being of analytic nature I find your posts thought provoking.

Protein does so much counteraction for our disease/addiction.


FredT said...

Thank you. It is good to think.